
Our Purpose
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Your strength is why we’re here. We know how exhausting the trial and error of treatment can be, and Compass was founded to change it. For those who have exhausted every option, we aim to offer a new way forward that’s rooted in a decade of rigorous clinical science.
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For decades, millions like you have been left to navigate a gray landscape with treatments that can be just as debilitating as the symptoms they tackle. We know conditions like yours are some of the toughest to treat, and that’s exactly why we’re focused on them. Our reason for being is to create new paths. Not by promising a miracle, but by acknowledging that the current standard of care has its limits. Because you deserve a way forward through this.
That’s why we’re striving to move psychiatry beyond chronic symptom management and toward true human restoration through the clinical application of new treatment approaches such as psychedelics. It’s about neuroplasticity and network reorganization: the biological capability of the brain to activate new pathways and connections. We believe our science has the power to help people break through the rigid thought loops that keep them feeling stuck. By grounding this work in rigorous science, we aim to provide the quality of mainstream medicine in a category that has been uncharted.
Ultimately, our clinical rigor and category leadership are a direct reflection of our personal understanding of what is at stake. Every discovery we make is dedicated to you, the caregivers and seekers of new options whose courage is our cause and whose resilience gives us purpose. We value doing things the right way, because we believe that everyone deserves a future filled with possibility. This science is personal to us—many of us have seen our own loved ones struggle with these same hurdles—and we’re working relentlessly to make these new pathways an accessible reality for you.
When you are diagnosed with TRD, it means your depression has resisted at least two courses of treatment. This resistance can increase risks to your health and often causes harm to your overall quality of life.¹ We’re dedicated to patients who have been failed by their treatments, and who need scientific innovation to rigorously pursue new possibilities.
Whether your story is of combat or assault, an accident or natural disaster, PTSD is a condition that may occur in people who have experienced traumatic events.² This constant state of high alert often complicates life for the patient and those closest to them. We are committed to anyone whose life has been obscured by PTSD’s devastation and seeks a path through it.
We encourage you to visit clinicaltrials.gov to learn more about our clinical trials.
Go to clinicaltrials.gov
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Information about independent organizations is provided as an additional resource for obtaining information related to mental health conditions. It does not indicate endorsement by Compass Pathways of an organization or its communications. Your healthcare team is your best source of information. All trademarks, brand names, and logos are property of their respective owners.

Our Purpose
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Learn more1. “Association of Treatment-Resistant Depression with Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study.” JAMA Psychiatry. 14 December 2022. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2799488
2. “What is PTSD?” American Psychiatric Association. Accessed, 27 May 2026. https://www.psychiatry.org/patients-families/ptsd/what-is-ptsd